2013 |
Lai, P.L., Hong, D.W., Chu, I.M*. “The influences of polycaprolactone-grafted nano-particles on the properties of polycaprolactone composites with enhanced osteo-conductivity”, Composite Sci. Technol. 83, 64-71(2013), 2013 |
2013 |
Lai, P.L., Lin, C.T.Y., Hong, D.W., Chang, Y.H., Chen, L.H., Chen, W.J., Chu, I.M.* “Development of bioactive thermosensitive polymer-ceramic composite as bone substitute”, Chem. Eng. Sci., 89, 133–141 (2013), 2013 |
2013 |
Shih, M.C., Tseng, S.H., Weng, Y.S., Chu, I.M., Liu, C.H*. “A gel-free multi-well micro-fluidic device utilizing surface tension for cell culturing”, Sensor. Actuator. B, 177, 295-307 (2013), 2013 |
2013 |
Peng, S., Yang, S.R., Peng, Y.S., Chu, I.M.*, “Evaluation of a mPEG-polyester-based hydrogel as cell carrier for chondrocytes”, J. Biomed. Mat. Res. A, 101, 3311-3319 (2013), 2013 |
2013 |
Peng, S., Yang, S.R., Peng, Y.S., Chu, I.M.*, “Evaluation of a mPEG-polyester-based hydrogel as cell carrier for chondrocytes”, J. Biomed. Mat. Res. A, 101, 3311-3319 (2013), 2013 |
2013 |
Lin, P.Y., Yang YC, Hung SH, Lee SY, Chu, I.M., Hwang, S.M*. “Cryopreservation of human embryonic stem cells by a programmed freezer with an oscillating magnetic field”, Cryobiology, 66, 256-260 (2013), 2013 |
2013 |
Lai, P.L., Hong, D.W., Liu, T.H., Lai, Z.T., Cheng, M.H., Chen, L.H., Chu, I.M*. “Validity of poly(1, 6-bis-(p-carboxyphenoxy hexane)-co-(sebacic anhydride)) copolymer in biomedical application”, J. Appl. Polym. Sci., 128, 3687-3695 (2013), 2013 |
2013 |
Chen, W.C. Wei, Y.H., Chu, I.M., Yao, C.L*. “Effect of chondroitin sulphate C on the in vitro and in vivo chondrogenesis of mesenchymal stem cells in crosslinked type II collagen scaffolds, J. Tissue Eng. Regen. Med., 7, 665–672 (2013), 2013 |
2013 |
Hwang Y.S, Chiang P.R, Hong W.H, Chiao C.C, Chu I.M, Hsiue, G.H., Shen, C.R*., ”Study in vivo intraocular biocompatibility of in situ gelation hydrogels: poly(2-ethyl oxazoline)-block-poly(ε-caprolactone)-block-poly(2-ethyl oxazoline) copolymer, matrigel and pluronic F127”. PLoS ONE 8(7): e67495. doi:10.1371/journal.pone.0067495 (2013), 2013 |
2013 |
Hong, D.W., Lai, P.L., Ku, K.L., Lai, Z.T., Chu, I.M*., “Biodegradable in situ gel-forming controlled vancomycin delivery system based on a thermosensitive mPEG-PLCPPA hydrogel “, Polym. Degrad. Stab. 98, 1578-1585 (2013), 2013 |
2013 |
Huang, J.J., Yang, S.R., Chu, I.M., Brey, E.M., Hsiao, H.Y., Cheng, M.H. “A comparative study of the chondrogenic potential between synthetic and natural scaffolds in an in vivo bioreactor”, Sci. Technol. Adv. Mater. 14, 054403 (2013), 2013 |
2013 |
Ko, C.Y., Ku, K.L., Yang, S.R., Lin, T.Y., Peng, S., Peng, Y.S., Cheng, M.H., Chu, I.M.*, “Cartilage formation through alterations of amphiphilicity of poly (ethylene glycol)-poly(caprolactone) copolymer hydrogels", RCS Adv., 3, 25769-25779 (2013), 2013 |
2013 |
Shih, M.C., Tseng, S.H., Weng, Y.S., Chu, I.M., Liu, C.H*. “A microfluidic device mimicking acinar concentration gradients across the liver acinus”, Biomed. Microdevice., 767-780 (2013), 2013 |
2013 |
Chiang, P.R., Lin, T.Y., Tsai, H.C., Chen, H.L., Liu, S.Y., Chen, F.R., Hwang, Y.S., Chu, I.M*.,”Thermosensitive hydrogel from oligopeptide-containing amphiphilic block copolymer: effect of peptide functional group on self-assembly and gelation behavior “, Langmuir, 51, 15981-15991(2013), 2013 |
2013 |
Lin, P.Y., Chu, I.M., Hwang, S.M.* “A synthetic peptide-acrylate surface for production of an insulin-producing cells from human embryonic stem cells", Stem Cell. Develop. Accepted (2013), 2013 |
2013 |
Hong, D.W., Lai, P.L., Ku, K.L., Lai, Z.T., Chu, I.M*.,”Novel thermosensitive hydrogels based on methoxy polyethylene glycol-co-poly(lactic acid-co-aromatic anhydride) for cefazolin delivery”, Nanomed. Accepted ( 2013), 2013 |
2013 |
Tsao, C.K., Ko, C.Y., Yang, S.R., Yang, C.Y., Brey, E.M., Huang, S., Chu, I.M., Cheng, M.H., “An ectopic approach for engineering a vascularized tracheal substitute”, Biomaterials, Accepted (2013), 2013 |
2013 |
Ko, C.Y., Ku, K.L., Yang, S.R., Lin, T.Y., Peng, S., Peng, Y.S., Cheng, M.H., Chu, I.M*., “In vitro and in vivo co-culture of chondrocytes and bone marrow stem cells in photo-crosslinked PCL–PEG–PCL hydrogels enhances cartilage formation”, J. Tissue. Eng. Regen. Med. Accepted (2013), 2013 |
2012 |
Hus, S.P. Chu, I.M*. “Thermo- and pH-responsive polymersomes of poly (α,β-N-substituted-DL-aspartamide)s", J. Appl. Polym. Sci., 125, 133-144 (2012), 2012 |
2012 |
Hong, D.W., Lai, P.L., Chu, I.M.* “Effect of mixing ceramics with a thermosensitive biodegradable hydrogel as composite graft”, Composites B, 8, 3088-3095, (2012), 2012 |
2012 |
Hus, S.P. Chu, I.M*., “Design of polyanionic nanocarriers based on modified poly (aspartic acid)s for oral administration: synthesis and characterization", J. Polym. Res. 19, 9913-9916 (2012), 2012 |
2012 |
Hong, D.W., Lai, P.L., Chu, I.M.* "Mixed micelles from methoxy poly(ethylene glycol)-polylactide and methoxy poly(ethylene glycol)-poly(sebacic anhydride) copolymers as drug carriers" J. React. Func. Polym., 72, 846-855 (2012), 2012 |
2012 |
Lai, P.L.*, Tai, C.L., Chu, I.M., Fu, T.S., Chen, L.H., Chen, W.J., “Hypothermic manipulation of bone cement can extend the handling time during vertebroplasty” BMC Musculoskelet. Disorder. 13, 198 (2012), 2012 |
2012 |
Huang, T.Y., Lu, W.C., Chu, I.M.* “A fermentation strategy for producing docosahexaenoic acid in Aurantiochytrium limacinum SR21 and increasing C22:6 proportions in total fatty acid”, Bioresource Technol., 123, 8-14 (2012), 2012 |
2011 |
Chen, W. C., Yao, C.L., Wei, Y.H., Chu, I.M.*, “Evaluating osteochondral defect repair potential of autologous rabbit bone marrow cells on type II collagen scaffold”, Cytotechnol., 63, 13–23 (2011), 2011 |
2011 |
Chen, W. C., Yao, C.L., Chu, I.M., Wei, Y.H*., “Compare the effects of chondrogenesis by culture of human mesenchymal stem cells with various type of the chondroitin sulfate C”, J. Biosci. Bioeng., 111, 226-231 (2011), 2011 |
2011 |
Chen, C.F., Shen, H.H., Lin, T.Y., Yu, Y.J., Chen, W.C., Chu, I.M.*, “Studies on the preparation and characterization of mPEG-polyester biodegradable bioglue for bone defect repair”, J. Med. Biol. Eng., 31, 13-17 (2011), 2011 |
2011 |
Hong, C.C*., Wang, C.Y., Peng, K.T., Chu, I.M., “A microfluidic chip platform with electrochemical carbon nanotube electrodes for pre-clinical evaluation of antibiotics nanocapsules”, Biosensor. Bioelectronic., 26, 3620-3626 (2011), 2011 |
2011 |
Hong, D.W., Liu, T.H., Chu, I.M*. “Encapsulation of curcumin by methoxy poly(ethylene glycol-b-aromatic anhydride) micelles", J. Appl. Polym. Sci., 122, 898-907 (2011), 2011 |
2011 |
Chen, W.C., Wei, Y.H., Huang, J.B., Chu, I.M., Yao, C.L.* “Biological effects of oligo- saccharide chondroitin sulfate C on human articular chondrocytes”, Biomed. Eng.-Appl. Basis Comm. 23, 245-252 (2011), 2011 |
2011 |
Chen, C.F., Huang, L.Y., Chu, I.M.* “Controlled release of cyclosporine A from biodegradable amphiphilic diblock copolymer sol-gel drug delivery system”, J. Med. Biol. Eng., 31, 177-183 (2011), 2011 |
2010 |
Chang, K.Y., Hung, L.H., Chu, I.M., Huang, L., Ko, C.S., Lee, Y.D.*, “The application of type II collagen and chondroitin sulfate grafted PCL porous scaffold in cartilage tissue engineering”, J. Biomed.Mater. Res. A , 92A, 712-723 (2010), 2010 |
2010 |
Wu, C.H., Ko, C.S., Huang, J.W., Huang, H.J., Chu, I.M.*, “Effects of exogenous glycosaminoglycans on human chondrocytes cultivated on type II collagen scaffolds”, J. Mater. Sci. Mater. Medicine, 21, 725-729 (2010), 2010 |
2010 |
Lin, K.L., Yang, D.Y., Chu, I.M., Cheng, F.C., Chen, C,J., Ho, S.P., Pan, H.C.*, "Dura seal as a ligature in the anastomosis of rat sciatic nerve gap injury", J. Surg. Res., 16, 101-110 (2010), 2010 |
2010 |
Peng, K.T.*, Chen, C.F., Chu, I.M., Li, Y.M., Hsu, W.H., Hsu, R.W.W., Chang, P.J. “Treatment of osteomyelitis with teicoplanin-encapsulated biodegradable thermosensitive hydrogel nanoparticles”, Biomaterials, 31, 5227-5236 (2010), 2010 |
2010 |
徐誠駿, 劉倉豪, 朱一民* “聚乙二醇-聚癸二酸酐與聚乙二醇-聚乳酸共聚物混合微胞於薑黃素之藥物輸送研究”, 化工技術, 207, 102-114 (2010), 2010 |
2010 |
Wang, H.M.*, Chen, C.Y., Chen, C.Y., Ho, M. L., Chou, Y.T., Chang, H.C., Wang, C.Z., Chu, I.M., “(-)-N-Formylanonaine from Michelia alba as a human tyrosinase inhibitor and antioxidant”, Bioorg. Med. Chem., 18, 5241-5247 (2010), 2010 |
2010 |
Chen, C.F., Lin, C.T.Y., Chu, I.M.*, “Study of novel biodegradable thermo- sensitive hydrogels of methoxy-poly(ethylene glycol-)block-polyester diblock copolymers”, Polym. Int., 59, 1428-1435 (2010), 2010 |
2009 |
K. Y. Chang, L. H. Hung, I. M. Chu, C. S. Ko, and Y. D. Lee, "The application of type II collagen and chondroitin sulfate grafted PCL porous scaffold in cartilage tissue engineering," Journal of Biomedical Materials Research Part A, vol. 92A, pp. 712-723, 2009., 2009 |
2009 |
T. W. Chen, S. M. Hwang, I. M. Chu, S. C. Hsu, T. B. Hsieh, and C. L. Yao, "Characterization and transplantation of induced megakaryocytes from hematopoietic stem cells for rapid platelet recovery by a two-step serum-free procedure," Experimental Hematology, vol. 37, pp. 1330-1339, Nov 2009., 2009 |
2009 |
T. W. Chen, C. L. Yao, I. M. Chu, T. L. Chuang, T. B. Hsieh, and S. M. Hwang, "Large generation of megakaryocytes from serum-free expanded human CD34(+) cells," Biochemical and Biophysical Research Communications, vol. 378, pp. 112-117, Jan 2 2009., 2009 |
2009 |
C. S. Ko, J. P. Huang, C. W. Huang, and I. M. Chu, "Type II collagen-chondroitin sulfate-hyaluronan scaffold cross-linked by genipin for cartilage tissue engineering," Journal of Bioscience and Bioengineering, vol. 107, pp. 177-182, Feb 2009., 2009 |
2009 |
Y. J. Lin, C. N. Yen, Y. C. Hu, Y. C. Wu, C. J. Liao, and I. M. Chu, "Chondrocytes culture in three-dimensional porous alginate scaffolds enhanced cell proliferation, matrix synthesis and gene expression," Journal of Biomedical Materials Research Part A, vol. 88A, pp. 23-33, Jan 2009., 2009 |
2009 |
T.H. Liu and I.M. Chu, "Degradation and localized drug release of polyanhydride microspheres and devices " Journal of Bioscience and Bioengineering, vol. 108, pp. S33-S34 2009., 2009 |
2009 |
Ko, C.S., Huang, J.P., Huang, C.W., Chu, I.M*., “Type II collagen-chondroitin sulfate-hyaluronan scaffold cross-linked by genipin for cartilage tissue engineering”, J. Biosci. Bioeng., 107, 177-182 (2009), 2009 |
2009 |
Ko, C.S., Huang, J.P., Huang, C.W., Chu, I.M*., “Type II collagen-chondroitin sulfate-hyaluronan scaffold cross-linked by genipin for cartilage tissue engineering”, J. Biosci. Bioeng., 107, 177-182 (2009), 2009 |
2009 |
Chen,T.W., Yao,C.L., Chu,I.M*., Chuang,T.L., Hsieh, T.B., Hwang,S.M., “Large generation of megakaryocytes from serum-free expanded human CD34(+) cells”, Biochem. Biophys. Res. Comm., 378, 112-117 (2009), 2009 |
2009 |
Lin, Y.J., Yen, C.N., Hu, Y.C., Wu, Y.C. Liao, C.J. Chu, I.M., “Chondrocytes culture in three-dimensional porous alginate scaffolds enhanced cell proliferation, matrix synthesis and gene expression”, J. Biomed. Mater. Res. A, 88A , 23-33 (2009), 2009 |
2008 |
Lee WC, Chu I.M., “Preparation and degradation behavior of polyanhydrides nanoparticles.” J Biomed Mater Res B Appl Biomater. 2008 Jan;84(1):138-46., 2008 |
2008 |
Wu, P.H., Nair GR, Chu, I.M., Wu, W.T., “High cell density cultivation of Escherichia coli with surface anchored transglucosidase for use as whole-cell biocatalyst for alpha-arbutin synthesis”, J Ind Microbiol Biotechnol. 35(2), 95-101 (2008), 2008 |
2008 |
Su, C.H., Fu, C.C., Chang, Y.C., Nair GR, Ye, J.L., Chu I.M., Wu, W.T., “Simultaneous estimation of chlorophyll a and lipid contents in microalgae by three-color analysis”, Biotechnol Bioeng. 99(4), 1034-1039 (2008), 2008 |
2008 |
Liu, S.H., Chu, I.M., Pan, I.H., ”Effects of hydroxybenzyl alcohols on melanogenesis in melanocyte-keratinocyte co-culture and monolayer culture of melanocytes”, J Enzyme Inhib Med Chem. 23(4), 526-534 (2008), 2008 |
2008 |
Chen, T.W., Yao, C.L., Chu, I.M., Chuang, T.L., Hsieh, T.B., Hwang, S.M.,”Large generation of megakaryocytes from serum-free expanded human CD34(+) cells”, Biochem Biophys Res Commun. 2008, 2008 |
2008 |
Chang Y.C , Chu,I.M , “Methoxy poly(ethylene glycol)-b-poly(valerolactone) diblock polymeric micelles for enhanced encapsulation and protection of camptothecin” , European Polymer Journal44 (2008) 3922–3930, 2008 |
2007 |
Su, W.T., Liao, Y.F., Chu, I.M., “Observation of fibroblast motility on a micro-grooved hydrophobic elastomer substrate with different geometric characteristics”, Micron, 38, 278–285 (2007), 2007 |
2007 |
Hsieh, H.J., Tung, K.Y., Nair, G.R., Chu, I.M., Wu, W.T., “Production of ascorbic acid glucoside by alginate-entrapped mycelia of Aspergillus niger”, Appl.Microbiol. Biotechnol., 77, 53-60 (2007), 2007 |
2007 |
Ko, C.S., Wu, C.H., Huang, H.H., Chu, I.M. “Genipin cross-linking of type II collagen- chondroitin sulfate-hyaluronan scaffold for articular cartilage therapy”, J. Med. Biol. Eng., 27, 7-14 (2007), 2007 |
2007 |
Liu, S.H., Pan, I.H., Chu, I.M. “Inhibitory effect of p-hydroxybenzyl alcohol on tyrosinase activity and melanogenesis”, Biol. Pharm. Bull., 30, 1135-1139 (2007), 2007 |
2007 |
Zheng, Y., Yeh, C.W., Yang, C.D., Jeng, S.S., Chu, I.M., ”On the local optimal solutions of metabolic regulatory networks using information guided genetic algorithm approach and clustering analysis “, J. Biotechol. 131, 159-167 (2007), 2007 |
2006 |
Yao, C.L., Feng, Y.H., Lin, X.Z., Chu, I.M., Hsieh, T.B., Hwang, S.M., “Characterization of serum-free ex vivo-expanded hematopoietic stem cells derived from human umbilical cord blood CD133(+) cells”, Stem Cells Develop., 15, 70-78 (2006), 2006 |
2006 |
Lee, W. C., Li, Y. C., Chu, I.M., “Amphiphilic poly(D,L-lactic acid)/poly(ethylene glycol)/ poly(D,L-lactic acid) nanogels for controlled release of hydrophobic drugs”, Macromol. Biosci., 6, 846–854 (2006), 2006 |
2006 |
Su, W.T., Chu, I.M., Yang, J.Y., Lin, C.D., “The geometric pattern of a pillared substrate influences the cell-process distribution and shapes of fibroblasts”, Micron, 37, 699-706 (2006), 2006 |
2005 |
Chan, C.K., Chu, I.M., “In vitro release of incorporated model compounds in poly(sebacic anhydride-co-ethylene glycol)”, Eur. Polymer J., 41,14031409 (2005), 2005 |
2004 |
W.T. Su, C.Y. Yang, C.D Lin and I.M. Chu, (2004). Control Cell Behavior on Physical Topographical Surface. Jap. J. Appl. Phys. 43:3906-3809., 2004 |
2004 |
C.K. Chan and I.M. Chu, (2004). In vitro degradation of poly(sebacic anhydride-co- ethylene glycol). Material. Chem. Phys. 88:59-66., 2004 |
2004 |
C.L. Yao, C.H. Liu, I.M. Chu, S.M Huang and Z.B. Hsieh, (2004). A systematic strategy to optimize ex vivo expansion medium for human hematopoietic stem cells derived from umbilical cord blood mononuclear cells. Exp. Hematol. 32:720-727, 2004 |
2004 |
Ko, C.S., Chu, I.M., “Immobilized cells biocatalyst for the production of S-acetylthio-2-methylpropanic acid”, Enzyme Microb. Technol. 35, 619-623 (2004), 2004 |
2004 |
C.K. Chan, I.M. Chu, C.F Ou and Y.W. Lin, (2004). Interfacial interactions and their influence to phase behavior in poly(vinyl pyrrolidone)/silica hybrid materials prepared by sol-gel process. Material Lett. 58:2243-2247, 2004 |
2003 |
朱一民, (2003) 生化分離程序. 生化產業技術概論, 吳文騰主編, 清大出版社, 新竹, Chapter 13., 2003 |
2003 |
C.K. Chan and I.M. Chu, (2003). Synthesis and Characterization of Branched Poly (sebacic Acid) using Glycerol. J. Appl. Polym. Sci. 90:886-893., 2003 |
2003 |
C.L. Yao, C.H. Liu, I.M. Chu, S.M Huang, Z.B.Hsieh, (2003). Factorial deign with steepest ascend path to optimize media for cord blood stem cell cultivation. Enzyme Microb. Technol. 33:343-352., 2003 |
2003 |
Chan, C.K., Chu, I.M., “Stability and depolymerization of poly(sebacic anhride) under high moisture environment”, J. Appl. Polym. Sci., 89 1423-1429 (2003), 2003 |
2003 |
S.C. Wu, C.H.Yu, C.W. Lin and I.M. Chu, (2003). The domain III fragment of Japanese encephalitis virus envelope protein: mouse immunogenicity and liposome adjuvanticity. Vaccine 21:2516-2522., 2003 |
2003 |
T.H Chou, S.C. Chen and I.M. Chu, (2003). Effect of Composition on the Stability of Liposomal Irinotecan Prepared by a pH Gradient Method. J. Biosci. Bioeng. 95:405-408., 2003 |
2003 |
Chou, T.H., Chu, I.M., ”Thermodynamic Characteristics of DSPC/DSPE-PEG2000 Mixed Monolayers on the Water Subphase at Different Temperatures”, Colloid.Surf. B 27, 333 – 344 (2003), 2003 |
2003 |
Chan, C.K., Chu, I.M., “Crystalline and Dynamic Mechanical Behaviors of Synthesized Poly(Sebacic Anhydride-co-Ethylene Glycol)”, Biomaterials, 24, 47-54 (2003), 2003 |